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Systems Neuroscientist at System1 Biosciences
San Francisco, CA, US

System1 Biosciences is revolutionizing drug discovery for brain disorders. Founded by professors from Columbia University and UCSF and experienced technologists, we combine biotechnology, neuroscience, robotics, and machine learning techniques. We employ AI-driven phenotypic screening to discover novel drugs for complex neurological and psychiatric diseases such as epilepsy, autism, and schizophrenia.

We are building a high-throughput experimental platform for the collection and analysis of modern large-scale neuroscience datasets including electrophysiology, functional imaging, imaging of cleared tissue, and closed-loop optogenetic perturbation.

We are seeking excellent systems neuroscientists to join our multidisciplinary team in our search to understand the complex biology of neurological and psychiatric disorders. This role is as a core driver of our scientific mission, exploring the cutting edge of experimental neurobiology applied to cerebral organoids.

In this position you will:

  • Design and develop experimental approaches to interrogate the functional activity of cerebral organoids to quantify disease biology
  • Interface with the stem cell biology and bioengineering teams to conceive and execute experiments
  • Collaborate with computational scientists to analyze and interpret neural activity data
  • Participate in team-wide projects as well as lead the design and delivery of independent initiatives
  • Publish results in high-impact journals

Our ideal candidate will have:

  • Academic publications in the field of systems and/or computational neuroscience; or 5+ years of industry experience in this area
  • Experience with synaptic, cellular, and circuit-level experimental neurobiology using electrophysiology, calcium imaging, optogenetics, or other quantitative approaches
  • Familiarity with statistical and computational methods for the analysis of experimental data

We offer competitive salaries and benefits, opportunities for professional growth, and an intellectually stimulating and fast-paced work environment.

If this excites you, then we are excited to hear from you! Please contact us and include your CV or résumé.

System1 Biosciences is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.

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